Journal Title：Toxicology In Vitro

Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. The Journal will focus on investigations that involve the development and validation of new in vitro methods, e.g. for prediction of toxic effects based on traditional and in silico modelling; on the use of methods in high-throughput toxicology and pharmacology; elucidation of mechanisms of toxic action; the application of genomics, transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. The Journal strongly encourages the submission of manuscripts that focus on the development of in vitro methods, their practical applications and regulatory use (e.g. in the areas of food components cosmetics, pharmaceuticals, pesticides, and industrial chemicals). Toxicology in Vitro discourages papers that record reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.

《體外毒理學(xué)》發(fā)表原創(chuàng)研究論文和評(píng)論，內(nèi)容涉及體外系統(tǒng)在評(píng)估或預(yù)測(cè)化學(xué)物質(zhì)毒性作用和闡明其作用機(jī)制方面的應(yīng)用和使用。這些體外技術(shù)包括利用細(xì)胞或組織培養(yǎng)物、分離細(xì)胞、組織切片、亞細(xì)胞部分、轉(zhuǎn)基因細(xì)胞培養(yǎng)物和轉(zhuǎn)基因生物細(xì)胞以及計(jì)算機(jī)模擬。該期刊將重點(diǎn)關(guān)注涉及開發(fā)和驗(yàn)證新體外方法的研究，例如基于傳統(tǒng)和計(jì)算機(jī)模擬預(yù)測(cè)毒性作用；高通量毒理學(xué)和藥理學(xué)方法的使用；毒性作用機(jī)制的闡明；基因組學(xué)、轉(zhuǎn)錄組學(xué)和蛋白質(zhì)組學(xué)在毒理學(xué)中的應(yīng)用，以及描述體外和體內(nèi)發(fā)現(xiàn)之間關(guān)系的比較研究。本期刊強(qiáng)烈鼓勵(lì)投稿關(guān)注體外方法的開發(fā)、其實(shí)際應(yīng)用和監(jiān)管用途（例如在食品成分化妝品、藥品、農(nóng)藥和工業(yè)化學(xué)品領(lǐng)域）。《體外毒理學(xué)》不鼓勵(lì)投稿記錄未經(jīng)化學(xué)鑒定的材料（如植物提取物或草藥）的毒理學(xué)效應(yīng)報(bào)告的論文。

Toxicology In Vitro創(chuàng)刊于1987年，由Elsevier Ltd出版商出版，收稿方向涵蓋醫(yī)學(xué) - 毒理學(xué)全領(lǐng)域，此刊是中等級(jí)別的SCI期刊，所以過(guò)審相對(duì)來(lái)講不是特別難，但是該刊專業(yè)認(rèn)可度不錯(cuò)，仍然是一本值得選擇的SCI期刊 。平均審稿速度 約2.0個(gè)月 約10.9周，影響因子指數(shù)2.6，該期刊近期沒有被列入國(guó)際期刊預(yù)警名單，廣大學(xué)者值得一試。